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What is Stem Filler* (Bio-Active) ?
Bio active autologous dermal filler.
Bio-Active Autologous Dermal Gel enriched with power of growth factors,matrix,activated platelets.Derived from patients own blood.Stays at localized injected area for upto 3 months,hence better efficacy and gradual release of growth factors,activated platelets & dermal fibroblasts activators at specific aesthetic indication area.
What is it made up of ?
- It is prepared from patient’s own blood.
- Bio Active Materials – Growth Factors like PDGF, VEGF, EGF & EGF-1
- Specialized tissue
- FIBRINO matrix
- Activated platelets
- Denaturized plasma gel protein
Mechanism of Action and Benefits.
- Volumizing effect (plasma gel)
- Viscosity of the filler can be tailor made to suit the specific aesthetic indication
- Autologous bio active blood contents stimulate natural dermal regeneration process
- Fibrin bundles trap platelets – help in sustained release of GF and localized volume stabilization, approximate duration of action of it’s effects is 3-5 months
- Trap platelets in gel synthesize and release bio active GF
- GF interacts with undifferentiated adipose cells and dermal fibro blast by attaching to the specific receptors promoting neocollagenesis – resulting soft tissue augmentationand reduction of wrinkles.
- GF also helps in synthesis of extra cellular matrix components like hyaluronic acid
- Contraction of myofibroblasts around wrinkles causes skin tightening and strengthening
Indications – What is it used for?
Stimulates cellular regeneration and collagen production
Fillers
Melasma
Post Acne Scar
Hand Feet Wrinkles
Hairloss
- Under eye tear trough deformity – Filling the hollowness, reducing fine lines, reducing hyper pigmentation, regenerative rejuvenation
- Acne Scar filling during subcision
- Volumize, contour and rejuvenate the face, neck and hands (like zygomatic bones, nasolabial lines and fine lines around eye and forehead)
- Melasma hyper pigmentation
- Skin glow and moisturizing
- Skin tightening
- Skin homogeneity & texture improvement
- Hair growth & hair thickening
Comparison with other fillers ( HA & Nano Fat fillers )
Benefits compared to synthetic fillers
- It is autologous and hence no allergic reaction
- It smoothly dissolves over time – no lumps like nano fat
- Cost effective – patient’s own blood
- Can be repeated every 3 months
- Very rare & uncommon side effects of synthetic filler like blindness, necrosis do not happen.
- Patients prefer Natural Fillers
Limitations
- Downtime 3-5 days (Hemosiderin in it may cause redness or blackness)
- Lesser volumizing effect than synthetic fillers – need to inject every 3-6 months
- Rare anaphylaxis can happen with either synthetic filler or PRP or PRF or GFC or Stem Filler
- Rare (though no case reported with stem filler yet) as in synthetic filler and nano fit filler pulmonary embolism or clot in blood related complication are less possible since it contains anti-coagulant
Bio Fillers & Stem Fillers
Nano Fat Fillers
Hyaluronic Filler
The Stem Filler can be applied to various areas, including full face, neck, feet,
scalp, hands, knees, and elbows. Treatment sessions are typically spaced as follows:
- 1st Treatment
- 2nd Treatment – 4 weeks later
- 3rd Treatment – 8 weeks later
Stem filler gel may last for 3-6 months. Immediate results are seen post injection
with better results every week. Volumizing effect is limited & lasts for few months
compared to synthetic filler lasting for 9-12 months.
- Treatment sessions options – as per indications :
- Monthly injections
- Quarterly injections
- Half yearly injections
- Yearly injections
Till when do the effects last? It’s effects last 3-6 months. Touch up procedure is required every 2-3 months
Is there any contra indication? On blood thinner, any skin infection or herpes infection, any keloid tendency.
Avoid any on any hemangioma, any corrective tissue disorder (Morpheus, SLE etc.)
Is there any age restriction? Above 20 years old if there is an indication
To know more about us our other online / offline workshops, courses in the field of stem dermatology, aesthetic medicine
and surgery, trichology and hair transplant, feel free to contact us on +91 9222222409 or jointdrs@stemfillers.com
- We are part of :
- International Society of Stem Dermatology
- Stem Fillers.com
- International Society of Aesthetic Medicine and Surgery (Isams.in)
- World Society of Hair Restoration & Surgery (www.worldsocietyofhairrestorationandsurgey.com)
- Indian society of Hair Restoration (www.ishr.co.in)